The 2019 First International Symposium on Instrumentation, Control, Artificial Intelligence, and Robotics (ICA-SYMP 2019) were attended by over 100 participants. The inaugural symposium was held on January 16-18, 2019 at the Faculty of Engineering, Chulalongkorn University and organized by the Automatic Control Systems Technical Committee of Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology Association (ECTI Association) with a joint collaboration of Thai Robotics Society (TRS) and Artificial Intelligence Association of Thailand (AAIT).